Description

P107 Retinoblastoma Gene Product-Related Protein is a high-purity biochemical reagent critical for advanced life science research and development. This protein plays a fundamental role in studies related to cell cycle regulation, tumor suppression, and gene function analysis. It is an essential tool for researchers and developers in the fields of oncology, molecular biology, and pharmaceutical discovery, enabling precise experimental work on cellular mechanisms.

Application

• Biochemical Research: Used as a key reagent in studies investigating the retinoblastoma (Rb) protein pathway, cell cycle control, and tumor suppressor mechanisms.
• Pharmaceutical Development: Serves as a critical reference standard and target protein in drug discovery programs focused on oncology and cell cycle inhibitors.
• Diagnostic Assay Development: Employed in the development and calibration of immunoassays (ELISA, Western Blot) for detecting Rb-related protein expression.
• Academic Research: Essential for university and institutional labs conducting fundamental research in cancer biology, apoptosis, and cellular senescence.
• Protein-Protein Interaction Studies: Utilized in pull-down assays, co-immunoprecipitation, and other techniques to map interaction partners within cellular signaling networks.
• Antibody Production & Validation: Acts as a high-quality immunogen and antigen for generating and validating specific antibodies against the retinoblastoma gene product.

Basic Information

Product Name	P107 Retinoblastoma Gene Product-Related Protein
CAS No.	146409-00-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	P107 Protein; Retinoblastoma-like Protein 1; RBL1; p107; p107-Rb; PRB1; Cyclin-Dependent Kinase Inhibitor p107; Rb-related protein p107; Retinoblastoma-associated protein
EINECS	Contact for details

Quality Control

Our P107 Retinoblastoma Gene Product-Related Protein is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation, and functional activity checks. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with rigorous research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture absorption. For optimal stability, aliquot into single-use quantities upon first thaw to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (SDS-PAGE)	> 90%
Purity (HPLC)	> 95%
Protein Content (BCA)	> 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Confirmed by functional assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.