Description

4-Iodobenzenepropanenitrile is a versatile aromatic nitrile building block featuring an iodine substituent. This compound is valued for its utility in cross-coupling reactions, such as Suzuki and Sonogashira couplings, enabling the synthesis of complex organic frameworks. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials and liquid crystal compounds.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex organic molecules and exploring new catalytic methodologies.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for biochemical research and diagnostic applications.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in specialty polymer chemistry.

Basic Information

Product Name	4-Iodobenzenepropanenitrile
CAS No.	146385-65-1
Molecular Formula	C9H8IN
Molecular Weight	257.07 g/mol
Synonyms	3-(4-Iodophenyl)propanenitrile; 4-Iodohydrocinnamitrile; (4-Iodophenyl)propionitrile; 3-(p-Iodophenyl)propionitrile; p-Iodohydrocinnamitrile; 4-Iodobenzylacetonitrile (common misnomer); β-(4-Iodophenyl)propionitrile; 146385-65-1
EINECS	Contact for details

Quality Control

Our 4-Iodobenzenepropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.