Description

tert-Butyl 3-Methylpiperidine-1-Carboxylate is a protected piperidine derivative that serves as a versatile and critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides that incorporate the 3-methylpiperidine moiety.
• Fine Chemical Production: Serves as a precursor in the manufacture of complex specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: Essential reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics & Bioactive Molecules: Used to introduce chiral, substituted piperidine scaffolds into molecules designed to mimic peptides or other bioactive structures.
• Ligand & Catalyst Development: Potential starting material for the synthesis of chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	tert-Butyl 3-Methylpiperidine-1-Carboxylate
CAS No.	146337-18-0
Molecular Formula	C11H21NO2
Molecular Weight	199.29 g/mol
Synonyms	1-Boc-3-methylpiperidine; 3-Methyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-methylpiperidine; tert-Butyl 3-methyl-1-piperidinecarboxylate; N-Boc-3-methylpiperidine; 3-Methylpiperidine-1-carboxylic acid tert-butyl ester; Boc-3-methylpiperidine; N-tert-Butoxycarbonyl-3-methylpiperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Methylpiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.