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(2S)-2-(Boc-Amino)Dodecanoic Acid CAS NO 146276-04-2


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CAS No.:146276-04-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2S)-2-(Boc-Amino)Dodecanoic Acid is a high-purity, chiral building block featuring a protected amino acid structure. This compound is essential for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
  • Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce a long-chain, hydrophobic amino acid residue with a protected amine.
  • Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
  • Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to modify the lipophilicity and chain length of candidate molecules.
  • Biochemical Tool: Used in the preparation of substrates or inhibitors for enzymatic studies and proteomics research.
  • Material Science: Potential monomer for creating specialized polymers with amino acid functionality.

Basic Information

Product Name (2S)-2-(Boc-Amino)Dodecanoic Acid
CAS No. 146276-04-2
Molecular Formula C₁₇H₃₃NO₄
Molecular Weight 315.45 g/mol
Synonyms Boc-Dodecanoic Acid; N-(tert-Butoxycarbonyl)-Dodecanoic Acid; (S)-2-((tert-Butoxycarbonyl)amino)dodecanoic acid; Boc-L-Aminododecanoic Acid; N-Boc-L-Aminolauric Acid; 2-[(2-Methylpropan-2-yl)oxycarbonylamino]dodecanoic acid; N-Boc-12-Aminododecanoic Acid; (S)-2-(tert-Butoxycarbonylamino)dodecanoic acid
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Quality Control

Our (2S)-2-(Boc-Amino)Dodecanoic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Chiral Purity (HPLC) ≥99.0% ee
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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