Description

1-Boc-3-Methoxypyrrolidine is a high-purity, protected pyrrolidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the orthogonal protection of the amine and hydroxyl functionalities, enabling selective deprotection and functionalization for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, including protease inhibitors and other bioactive compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry.
• Peptidomimetics & PROTACs: Serves as a crucial scaffold in the design of peptide mimics and proteolysis-targeting chimeras (PROTACs) for drug discovery.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic routes in organic chemistry.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	1-Boc-3-Methoxypyrrolidine
CAS No.	146257-03-6
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	tert-Butyl 3-methoxypyrrolidine-1-carboxylate; 3-Methoxy-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-methoxypyrrolidine; N-Boc-3-methoxypyrrolidine; Boc-3-methoxypyrrolidine; 1-Boc-3-methoxy-pyrrolidine; Pyrrolidine, 3-methoxy-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Methoxypyrrolidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to meet the stringent requirements of pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.