Description

n-Hydroxy-4-Phosphonobutanamide is a specialized organophosphorus compound featuring a hydroxamic acid moiety. This unique bifunctional structure makes it a valuable intermediate and chelating agent for advanced chemical synthesis and industrial processes. It is primarily utilized by manufacturers in the pharmaceutical, agrochemical, and water treatment sectors for its metal-binding properties and role in creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition where the phosphonate and hydroxamate groups are critical for bioactivity.
• Agrochemical Synthesis: Serves as a key building block for developing new herbicides and plant growth regulators with enhanced efficacy and environmental profiles.
• Industrial Water Treatment: Acts as a high-performance scale and corrosion inhibitor in cooling water and boiler systems due to its strong chelation of divalent metal ions like calcium and magnesium.
• Metal Chelation & Decontamination: Employed in formulations for metal ion sequestration, surface treatment, and in decontamination processes for specific industrial effluents.
• Research & Development: A crucial reagent in academic and industrial R&D for studying phosphonate chemistry, metalloenzyme inhibition, and material surface modification.

Basic Information

Product Name	n-Hydroxy-4-Phosphonobutanamide
CAS No.	146086-80-8
Molecular Formula	C4H10NO5P
Molecular Weight	183.10 g/mol
Synonyms	4-Phosphonobutyrohydroxamic Acid; N-Hydroxy-4-phosphonobutyramide; 4-(Hydroxyamino)-4-oxobutylphosphonic Acid; Butanamide, N-hydroxy-4-phosphono-; PBHA; HPA; Phosphonobutanehydroxamic Acid
EINECS	Contact for details

Quality Control

Our n-Hydroxy-4-Phosphonobutanamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters are provided with every shipment. We support compliance with relevant regulatory frameworks for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.