Description

Boc-N,2-Dimethylalanine is a protected amino acid derivative of significant importance in synthetic organic and medicinal chemistry. This compound serves as a crucial building block for the synthesis of peptides and peptidomimetics, offering enhanced stability and controlled reactivity during complex multi-step reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a dimethylalanine residue with an N-terminal tert-butoxycarbonyl (Boc) protecting group.
• Proteomics Research: Employed in the design and study of modified peptides to investigate protein structure, function, and interactions.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for diagnostic and therapeutic applications.
• Agrochemical Development: Serves as a synthetic intermediate in creating novel pesticides and herbicides with peptide-like structures.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and for exploring new chemical spaces in drug discovery.

Basic Information

Product Name	Boc-N,2-Dimethylalanine
CAS No.	146000-39-7
Molecular Formula	C₁₀H₁₉NO₄
Molecular Weight	217.26 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2,2-dimethylalanine; Boc-Dimethylalanine; Boc-2,2-Dimethyl-Ala-OH; (2,2-Dimethyl-1-((2-methylpropan-2-yl)oxycarbonylamino)propyl)carboxylic Acid; N-Boc-2,2-Dimethylglycine; tert-Butyl (2,2-dimethyl-1-carboxyethyl)carbamate; N-(tert-Butoxycarbonyl)-α,α-dimethylglycine; Boc-Aib-OH (commonly associated with 2-aminoisobutyric acid derivatives)
EINECS	Contact for details

Quality Control

Our Boc-N,2-Dimethylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, to ensure it meets high-grade specifications for research and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.