Description

4-Bromo-1-Naphthaleneboronic Acid CAS NO 145965-14-6 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs), liquid crystal materials, and organic electronic components.

Application

• Pharmaceutical Intermediate: A key synthon for constructing naphthalene-based scaffolds in drug discovery and development of potential therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides with specific activity profiles.
• Material Science: Serves as a precursor for organic semiconductors, liquid crystals, and other functional materials requiring precise molecular architecture.
• Chemical Research: A valuable reagent in academic and industrial R&D for methodology development and library synthesis via palladium-catalyzed cross-coupling.
• Ligand Synthesis: Can be utilized to create sophisticated boronic acid-based ligands for catalysis or sensing applications.

Basic Information

Product Name	4-Bromo-1-Naphthaleneboronic Acid
CAS No.	145965-14-6
Molecular Formula	C10H8BBrO2
Molecular Weight	250.89 g/mol
Synonyms	(4-Bromonaphthalen-1-yl)boronic acid; 1-Naphthaleneboronic acid, 4-bromo-; 4-Bromo-1-naphthylboronic acid; 4-Bromonaphthalene-1-boronic acid; B-(4-Bromo-1-naphthyl)boronic acid; 4-Br-1-NapB(OH)2; 4-Bromo-1-NBA
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Naphthaleneboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is characterized by NMR (1H, 11B, 13C) and mass spectrometry for identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality management system supports cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.