Description

Rho4 Protein CAS NO 145941-28-2 is a high-purity, biologically active protein used in advanced life science research and development. This compound is critical for studying cellular signaling pathways, particularly those involving GTPase activity and cytoskeletal dynamics. It is an essential reagent for pharmaceutical companies, academic research institutions, and CROs focused on oncology, neurology, and cardiovascular disease research.

Application

• Biochemical Research: Used as a key reagent in enzymatic assays to study Rho GTPase signaling mechanisms and protein-protein interactions.
• Drug Discovery & Screening: Serves as a target protein in high-throughput screening (HTS) platforms to identify novel therapeutic compounds for cancer and other diseases.
• Diagnostic Development: Employed in the development of diagnostic kits and assays for detecting specific cellular pathway activities.
• Cell Biology Studies: Essential for in vitro studies investigating cell motility, adhesion, and morphology changes.
• Protein-Protein Interaction Analysis: Used in pull-down assays, co-immunoprecipitation, and surface plasmon resonance (SPR) to map interaction networks.
• Antibody Production & Validation: Acts as a high-quality antigen for generating and validating specific antibodies.

Basic Information

Product Name	Rho4 Protein
CAS No.	145941-28-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rho-related GTP-binding protein Rho4; Rho4 GTPase; RHO4; TC10-like GTP-binding protein; ARH4; Rho family GTPase 4; Rho-4; p23 Rho4
EINECS	Contact for details

Quality Control

Our Rho4 Protein is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including SDS-PAGE, Western Blot, and functional activity assays, to ensure high purity and biological activity. Certificates of Analysis (COA) detailing purity, concentration, endotoxin levels, and specific activity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Purity (SDS-PAGE)	> 95%
Identification (Western Blot)	Positive
Endotoxin Level	< 1.0 EU/µg
Biological Activity (GTPase Assay)	Fully active
Protein Concentration	As per COA (typically 0.1 - 1.0 mg/mL)
Buffer Composition	Tris, NaCl, Glycerol, DTT (or as specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.