Description

Rho3 Protein CAS NO 145941-27-1 is a high-purity, biologically active protein used in advanced biochemical research and development. This product is critical for studying cellular signaling pathways, particularly those involving GTPase activity and cytoskeletal dynamics. It is an essential reagent for pharmaceutical companies, academic research institutions, and diagnostic developers focused on oncology, neurology, and cell biology.

Application

• Biochemical Research: Used as a key substrate or target protein in enzymatic assays to study Rho GTPase signaling mechanisms.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) platforms to identify novel inhibitors or activators for therapeutic development.
• Diagnostic Development: Serves as a reference standard or antigen in the development of immunoassays and diagnostic kits.
• Academic Studies: Facilitates fundamental research into cell motility, morphology, and intracellular transport processes.
• Protein-Protein Interaction Studies: Utilized in pull-down assays, co-immunoprecipitation, and surface plasmon resonance (SPR) to map interaction networks.
• Enzyme Kinetics: Provides a well-defined protein for kinetic analysis of GTP hydrolysis and nucleotide exchange.

Basic Information

Product Name	Rho3 Protein
CAS No.	145941-27-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rho-related GTP-binding protein Rho3; RHO3; Rho3 GTPase; TC10-like GTP-binding protein; Rho family small GTPase 3; p29
EINECS	Contact for details

Quality Control

Our Rho3 Protein is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, functional activity assays, and endotoxin level checks. Certificates of Analysis (COA) detailing identity, purity, and biological activity are available upon request to ensure it meets your specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to expected molecular weight
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity (GTPase Assay)	Fully active, lot-specific data provided
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate assay buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.