Description

Acetamide, n-[(1R)-2-Hydroxy-1-Methylethyl]- is a chiral acetamide derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block, enabling the construction of complex molecules with precise stereochemistry for high-value applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where specific stereochemistry is crucial for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring enantiomeric purity.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and stereoselective synthesis.

Basic Information

Product Name	Acetamide, n-[(1R)-2-Hydroxy-1-Methylethyl]-
CAS No.	145842-51-9
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	(R)-N-(2-Hydroxypropyl)acetamide; (R)-1-Acetamidopropan-2-ol; (R)-2-Hydroxypropylacetamide; N-[(1R)-2-Hydroxy-1-methylethyl]acetamide; (R)-Acetamide, N-(2-hydroxypropyl)-; (R)-N-Acetyl-2-aminopropanol; (R)-2-Acetamido-1-propanol; (R)-1-(Acetylamino)-2-propanol
EINECS	Contact for details

Quality Control

Our Acetamide, n-[(1R)-2-Hydroxy-1-Methylethyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.