Description

Detumomab is a monoclonal antibody specifically engineered for targeted therapeutic applications. This compound is of significant value in the research and development of novel immunotherapies and diagnostic agents. It is primarily utilized by pharmaceutical developers, biotechnology research institutions, and clinical laboratories focused on oncology and immunological disorders. Detumomab CAS NO 145832-33-3 represents a high-purity biological reagent critical for advancing precision medicine.

Application

• Primary research and development of targeted cancer immunotherapies.
• Pre-clinical studies for evaluating antibody-drug conjugate (ADC) efficacy and safety.
• Use as a critical reference standard in bioanalytical method development and validation.
• Component in diagnostic assay development for specific antigen detection.
• Tool compound for studying cell signaling pathways and tumor microenvironment interactions.
• Investigational agent in combination therapy research for enhanced treatment outcomes.

Basic Information

Product Name	Detumomab
CAS No.	145832-33-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Anti-CD19 Monoclonal Antibody (Murine); Monoclonal Antibody CD19; Anti-B-Lymphocyte Antigen CD19; B4; Leu-12; CVID3; Immunoglobulin G1, anti-(mouse CD19 antigen) (mouse monoclonal B43 γ1-chain), disulfide with mouse monoclonal B43 κ-chain, dimer
EINECS	Contact for details

Quality Control

Our Detumomab is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC, identity confirmation, and potency testing. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting and freezing at -20°C or below to maintain stability. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/ELISA)	Complies
Purity (SDS-PAGE / SEC-HPLC)	≥ 95%
Protein Content (UV)	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/mg
Biological Activity (Cell-based assay)	Contact for details
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.