Description

4-Bromo-2-Fluoro-1-(2,2,2-Trifluoroethoxy)Benzene is a high-value fluorinated and brominated aromatic building block, essential for introducing specific halogenated motifs into complex molecular architectures. Its precise structure makes it a critical intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine and bromine atoms to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the halogenated phenyl ether structure can contribute to specific biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to desired dielectric and optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to construct complex, multi-functional aromatic systems.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating novel fluorinated compounds.

Basic Information

Item	Details
Product Name	4-Bromo-2-Fluoro-1-(2,2,2-Trifluoroethoxy)Benzene
CAS No.	145767-77-7
Molecular Formula	C8H5BrF4O
Molecular Weight	273.03 g/mol
Synonyms	1-Bromo-4-(2,2,2-trifluoroethoxy)-2-fluorobenzene; 2-Fluoro-4-bromo-1-(2,2,2-trifluoroethoxy)benzene; 4-Bromo-2-fluoro-1-(2,2,2-trifluoroethoxy)benzene; 2-Fluoro-4-bromophenyl 2,2,2-trifluoroethyl ether; 145767-77-7; 4-Bromo-2-fluorophenyl trifluoroethyl ether
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoro-1-(2,2,2-Trifluoroethoxy)Benzene is produced and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.