Description

α-Amino-n-Methyl-1-(Triphenylmethyl)-1H-Imidazole-4-Propanamide is a specialized, high-purity chemical building block featuring a protected imidazole core. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and complex heterocyclic molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific molecular functionality with high selectivity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially those targeting enzyme inhibition.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics due to its amino acid-like structure with a protected amine.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, or insecticides with specific biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis or organocatalysts.
• Chemical Biology Probes: Utilized in the construction of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring a protected, functionalized imidazole derivative.

Basic Information

Product Name	α-Amino-n-Methyl-1-(Triphenylmethyl)-1H-Imidazole-4-Propanamide
CAS No.	145695-69-8
Molecular Formula	C27H28N4O
Molecular Weight	424.54 g/mol
Synonyms	1H-Imidazole-4-propanamide, α-amino-N-methyl-1-(triphenylmethyl)-; 1-Trityl-α-amino-N-methyl-1H-imidazole-4-propanamide; N-Methyl-α-amino-1-trityl-1H-imidazole-4-propanamide; 4-(2-Amino-2-methylaminocarbonylethyl)-1-tritylimidazole; α-Amino-N-methyl-1-trityl-1H-imidazole-4-propanamide; 1-Trityl-α-amino-N-methylimidazole-4-propionamide
EINECS	Contact for details

Quality Control

Our α-Amino-n-Methyl-1-(Triphenylmethyl)-1H-Imidazole-4-Propanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.