Description

(3S,4S)-(-)-Bis(Diphenylphosphino)Pyrrolidine CAS NO 145693-67-0 is a high-value, chiral bidentate phosphine ligand widely used in asymmetric catalysis. Its significance lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing single-enantiomer compounds. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for synthesizing advanced intermediates and active ingredients.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediates.
• Catalyst component for enantioselective C-C bond formation, such as cross-coupling and allylic substitution.
• Key reagent in the synthesis of chiral active pharmaceutical ingredients (APIs) and agrochemicals.
• Used in academic and industrial research for developing new catalytic asymmetric transformations.
• Facilitates the production of enantiomerically pure flavors, fragrances, and specialty materials.
• Employed in process chemistry for scaling up enantioselective catalytic processes.

Basic Information

Product Name	(3S,4S)-(-)-Bis(Diphenylphosphino)Pyrrolidine
CAS No.	145693-67-0
Molecular Formula	C32H29NP2
Molecular Weight	489.53 g/mol
Synonyms	(3S,4S)-(-)-2,5-Bis(diphenylphosphino)pyrrolidine; (S,S)-(-)-2,5-Bis(diphenylphosphino)pyrrolidine; (S,S)-BDPP; (S,S)-Bis(diphenylphosphino)pyrrolidine; (3S,4S)-BDPP; (S,S)-Me-DuPhos Pyrrolidine Analog; ChiraPhos; Pyrrolidine-based chiral diphosphine ligand
EINECS	Contact for details

Quality Control

Our (3S,4S)-(-)-Bis(Diphenylphosphino)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay by HPLC, to ensure it meets the high standards required for asymmetric synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent performance and lot-to-lot reproducibility for your critical catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.