Description

2,3-Difluorophenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the phenyl ring, which can dramatically alter the electronic properties, metabolic stability, and bioavailability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electro-optical materials.
• Chemical Research: A valuable reagent for studying structure-activity relationships (SAR) and for introducing the 2,3-difluorophenylacetic acid moiety into more complex molecular architectures.
• Peptide Mimetics: Used in the design and synthesis of peptidomimetics and other bioactive compounds where the acetic acid side chain provides a handle for further derivatization.

Basic Information

Item	Detail
Product Name	2,3-Difluorophenylacetic Acid
CAS No.	145689-41-4
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	(2,3-Difluorophenyl)acetic Acid; 2,3-Difluorobenzeneacetic Acid; α-(2,3-Difluorophenyl)acetic Acid; 2-(2,3-Difluorophenyl)acetic Acid; NSC 339063; 2,3-DFPA; 2,3-Difluoro-α-toluic Acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluorophenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.