Description

Methyl 2,3,4,5,6-Pentafluorophenylacetate is a high-purity fluorinated aromatic ester building block, valued for its role as a versatile synthon in advanced organic synthesis. Its core value proposition lies in introducing the highly stable and lipophilic pentafluorophenyl group into target molecules, which can significantly alter their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic moieties to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the pentafluorophenyl group can improve efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic displays and organic light-emitting diodes, contributing to improved performance and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique characteristics such as enhanced chemical resistance, lower surface energy, or altered refractive index.
• Chemical Research & Development: A critical reagent in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and the creation of novel chemical entities.
• Fluorinated Dye & Pigment Precursor: Utilized in the synthesis of specialized dyes and pigments with enhanced light-fastness and unique chromatic properties.

Basic Information

Product Name	Methyl 2,3,4,5,6-Pentafluorophenylacetate
CAS No.	145682-85-5
Molecular Formula	C9H5F5O2
Molecular Weight	240.13 g/mol
Synonyms	Methyl Pentafluorophenylacetate; Methyl (Pentafluorophenyl)acetate; 2,3,4,5,6-Pentafluorophenylacetic Acid Methyl Ester; Methyl α-Pentafluorophenylacetate; Pentafluorophenylacetic Acid Methyl Ester; Methyl Perfluorophenylacetate; MFCD03427400; Methyl 2-(Pentafluorophenyl)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2,3,4,5,6-Pentafluorophenylacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with relevant regulatory frameworks for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.