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2-{[(tert-Butoxy)Carbonyl](Prop-2-En-1- Yl)Amino}Acetic Acid CAS NO 145618-68-4


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CAS No.:145618-68-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-{[(tert-Butoxy)Carbonyl](Prop-2-En-1- Yl)Amino}Acetic Acid is a specialized Boc-protected amino acid derivative featuring a reactive allyl group. This compound matters as a versatile and high-purity building block for the synthesis of complex molecules, enabling precise chemical modifications. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced organic synthesis, peptide chemistry, and the development of novel active pharmaceutical ingredients (APIs) and linkers for bioconjugation.

Application

  • Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
  • Peptide Chemistry: Used as a protected amino acid derivative for the solid-phase and solution-phase synthesis of modified peptides and peptidomimetics.
  • Bioconjugation Linker: Serves as a precursor for creating functionalized linkers used to attach drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles.
  • Organic Synthesis Building Block: The reactive allyl and Boc-protected amine groups allow for diverse chemical transformations, making it valuable for constructing heterocycles and other complex organic scaffolds.
  • Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines in multi-functional molecule synthesis.
  • Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities for screening.

Basic Information

Product Name 2-{[(tert-Butoxy)Carbonyl](Prop-2-En-1- Yl)Amino}Acetic Acid
CAS No. 145618-68-4
Molecular Formula C10H17NO4
Molecular Weight 215.25 g/mol
Synonyms N-Allyl-N-(Boc)glycine; Boc-N-allylglycine; (tert-Butoxycarbonyl)(allyl)aminoacetic Acid; 2-[(tert-Butoxycarbonyl)(allyl)amino]acetic Acid; N-(tert-Butoxycarbonyl)-N-allylglycine; Allyl-Boc-glycine; N-Allyl-N-(tert-butoxycarbonyl)glycine; 2-{[(tert-Butoxy)carbonyl](prop-2-en-1-yl)amino}acetic acid
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Quality Control

Our 2-{[(tert-Butoxy)Carbonyl](Prop-2-En-1- Yl)Amino}Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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