Description

(R)-3-(3-Methylbutanoyl)-4-Benzyloxazolidin-2-One is a high-purity chiral auxiliary and synthetic intermediate of significant importance in asymmetric organic synthesis. Its value lies in its ability to direct stereoselective reactions, enabling the production of enantiomerically pure pharmaceutical compounds and fine chemicals. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for complex molecule construction.

Application

• Asymmetric Synthesis: As a chiral auxiliary for the stereocontrolled formation of carbon-carbon and carbon-heteroatom bonds.
• Pharmaceutical Intermediates: A key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific (R)-configured stereocenters.
• Agrochemical Development: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Process Chemistry: Employed in route scouting and scale-up for the commercial manufacturing of chiral compounds.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis studies.
• Fine Chemical Production: For the synthesis of specialty chemicals, flavors, and fragrances where optical purity is critical.

Basic Information

Product Name	(R)-3-(3-Methylbutanoyl)-4-Benzyloxazolidin-2-One
CAS No.	145589-03-3
Molecular Formula	C15H19NO3
Molecular Weight	261.32 g/mol
Synonyms	(R)-4-Benzyl-3-(3-methylbutanoyl)oxazolidin-2-one; (R)-4-Benzyl-3-(3-methylbutyryl)-2-oxazolidinone; (R)-3-Isobutyryl-4-benzyloxazolidin-2-one (common name); (R)-3-(3-Methylbutyryl)-4-benzyl-2-oxazolidinone; (R)-N-Benzyl-3-(3-methylbutanoyl)oxazolidin-2-one; Evans Auxiliary derivative; Chiral oxazolidinone auxiliary
EINECS	Contact for details

Quality Control

Our (R)-3-(3-Methylbutanoyl)-4-Benzyloxazolidin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high optical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and standard purity assays. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.