Description

Sporozoite-Surface Protein 2, Plasmodium Yoelli CAS NO 145559-08-6 is a recombinant protein antigen derived from the rodent malaria parasite *Plasmodium yoelii*. This protein is a critical research tool for studying the biology of malaria sporozoites, the infective stage transmitted by mosquitoes, and for evaluating vaccine candidates. It is essential for researchers and developers in the fields of parasitology, immunology, and vaccine development who require high-purity, well-characterized antigens for immunoassays, antibody production, and protective efficacy studies.

Application

• Malaria Vaccine Research & Development: Used as a key antigen for immunogenicity testing and the evaluation of pre-erythrocytic stage vaccine candidates.
• Immunoassay Development: Serves as a coating antigen or standard in ELISA (Enzyme-Linked Immunosorbent Assay) and other serological assays to detect specific antibodies.
• Antibody Production & Characterization: Employed for the immunization of laboratory animals to generate polyclonal or monoclonal antibodies against *P. yoelii* sporozoites.
• Parasite-Host Interaction Studies: Facilitates research into the molecular mechanisms of sporozoite invasion of hepatocytes and host immune responses.
• Diagnostic Tool Development: Acts as a reference material in the development of diagnostic tests for malaria research models.
• Academic & Institutional Research: Provides a standardized reagent for basic research in infectious diseases and comparative parasitology.

Basic Information

Product Name	Sporozoite-Surface Protein 2, Plasmodium Yoelli
CAS No.	145559-08-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PySSP2; Plasmodium yoelii Sporozoite Surface Protein 2; P. yoelii Circumsporozoite Protein (CSP) homolog; Recombinant PySSP2; Malaria sporozoite antigen; PyCSP; P.yoelii antigen
EINECS	Contact for details

Quality Control

Every batch of Sporozoite-Surface Protein 2, Plasmodium Yoelli is produced and purified under stringent conditions to ensure high biological activity and lot-to-lot consistency. Our quality assurance includes comprehensive analytical testing for identity, purity, and stability. A Certificate of Analysis (COA) detailing specifications such as purity (by SDS-PAGE and HPLC), endotoxin level, protein concentration, and biological activity is provided with each shipment to support your research compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single major band at expected molecular weight
Purity (HPLC)	≥ 90%
Protein Content (BCA)	≥ 95% of stated weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Confirmed by immunoassay (e.g., ELISA with reference serum)
Solubility	Soluble in PBS or suitable aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.