Description

Lactococcin B is a ribosomally synthesized and post-translationally modified peptide (RiPP) bacteriocin produced by certain strains of *Lactococcus lactis*. This compound matters for its potent and narrow-spectrum antimicrobial activity, specifically targeting other lactic acid bacteria, which makes it a valuable tool for microbial population control in complex fermentations. It is needed by researchers in microbiology and food science, as well as by producers in the dairy and probiotic industries, for applications ranging from starter culture optimization to biopreservation.

Application

• Starter Culture Management: Used in dairy fermentations to inhibit competing or phage-carrying bacterial strains, ensuring the dominance and purity of desired starter cultures.
• Food Biopreservation: Investigated as a natural preservative agent in fermented foods to control spoilage microbiota and enhance shelf life.
• Probiotic Research: Serves as a selective agent in laboratory studies to modulate and study the composition of complex microbial communities, including gut microbiota models.
• Bacteriocin Mechanism Studies: A key model compound in academic and industrial research for understanding the structure, function, and mode of action of Class II bacteriocins.
• Microbial Fermentation Optimization: Applied in controlled fermentation processes to direct metabolic pathways by selectively removing specific bacterial populations.
• Diagnostic Tool Development: Utilized in the development of selective microbiological assays and detection methods for specific bacterial species.

Basic Information

Product Name	Lactococcin B
CAS No.	145421-14-3
Molecular Formula	C186H301N55O57S2
Molecular Weight	~4230.9 g/mol
Synonyms	Lactococcin B; Lactococcin-B; Bacteriocin Lactococcin B; Anti-lacticin bacteriocin; Lactococcus lactis subsp. cremoris bacteriocin; LcnB; Class IIb bacteriocin Lactococcin B
EINECS	Contact for details

Quality Control

Our Lactococcin B is produced and handled under strict quality protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation, to ensure consistent biological activity and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA), detailing purity, potency, and analytical results, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Biological Activity	Defined inhibitory units/mg (Contact for details)
Endotoxin Level	< 10 EU/mg
Solubility	Soluble in aqueous buffers, mild acids

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.