Description

Coronin Protein CAS NO 145420-64-0 is a high-purity, biologically active protein crucial for cellular research and development. This protein plays a fundamental role in regulating the actin cytoskeleton, impacting essential cellular processes such as migration, phagocytosis, and vesicular trafficking. It is an indispensable reagent for researchers and developers in the fields of cell biology, immunology, and neuroscience, as well as for biopharmaceutical companies investigating novel therapeutic targets.

Application

• Biomedical Research: Used as a key reagent in studies of actin cytoskeleton dynamics, cell motility, and intracellular signaling pathways.
• Drug Discovery & Development: Serves as a target protein for screening compounds in neurodegenerative disease and immunology research programs.
• Diagnostic Assay Development: Employed in the development of ELISA and other immunoassays to detect and quantify cellular responses.
• Protein-Protein Interaction Studies: Essential for pull-down assays, co-immunoprecipitation, and other techniques to map interaction networks.
• Cell Culture & Functional Studies: Added to cell culture systems to study its effects on macrophage function, neuronal development, and other specialized cell behaviors.
• Antibody Production & Validation: Acts as a high-quality immunogen for generating specific monoclonal or polyclonal antibodies.

Basic Information

Product Name	Coronin Protein
CAS No.	145420-64-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Coronin-1A; CORO1A; Tryptophan-Aspartic acid (WD) repeat-containing protein Coronin-1A; p57; Actin-binding protein Coronin-1A; Coronin-like protein p57; CLABP; WD repeat-containing protein 1A
EINECS	Contact for details

Quality Control

Our Coronin Protein is produced under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes rigorous analytical testing, including SDS-PAGE, Western Blot, and functional activity assays, to verify purity, identity, and performance. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE/Western Blot)	Complies
Purity (SDS-PAGE)	> 95%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell-based assay)	Complies
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.