Description

Glycoprotein E, Flavivirus is a critical viral envelope protein essential for host cell receptor binding and membrane fusion. This recombinant protein is a vital reagent for the research, development, and quality control of diagnostics, therapeutics, and vaccines targeting flaviviruses. It is primarily utilized by biotechnology firms, diagnostic manufacturers, and academic research institutions engaged in virology and immunology.

Application

• Diagnostic Development: Key antigen for ELISA, lateral flow assays, and other immunoassays to detect flavivirus-specific antibodies (e.g., for Dengue, Zika, West Nile virus).
• Vaccine Research: Essential component for immunogenicity studies, epitope mapping, and as a reference standard in vaccine candidate evaluation.
• Therapeutic Antibody Screening: Target protein for the discovery and characterization of neutralizing monoclonal antibodies.
• Serological Studies: Used as a coating antigen to assess immune response and seroprevalence in epidemiological research.
• Quality Control (QC): Serves as a reference standard for lot-to-lot consistency testing of commercial diagnostic kits.
• Structural Biology: Protein for X-ray crystallography or cryo-EM studies to understand virus-host interactions.

Basic Information

Product Name	Glycoprotein E, Flavivirus
CAS No.	145420-18-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Flavivirus Envelope Glycoprotein E; Flavivirus E Protein; Viral Envelope Protein E; Dengue Virus Envelope Protein; Zika Virus E Protein; West Nile Virus Glycoprotein E; Recombinant Flavivirus E Glycoprotein; Env Protein
EINECS	Contact for details

Quality Control

Our Glycoprotein E, Flavivirus is produced under stringent quality systems. Each batch undergoes comprehensive analytical testing, including SDS-PAGE, Western Blot, and HPLC for purity and identity verification, ensuring it meets rigorous research-grade specifications. Certificates of Analysis (COA) detailing purity, endotoxin levels, and biological activity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This material is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot upon receipt for optimal preservation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solution
Identification (SDS-PAGE/Western Blot)	Conforms
Purity (HPLC)	> 90%
Protein Content	> 95% of total
Endotoxin Level	< 1.0 EU/µg
Biological Activity (ELISA Binding)	Conforms
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.