Description

5-Thiazolecarbonitrile, 4-Chloro- is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the reactive nitrile and chloro substituents on the thiazole ring, which allow for selective functionalization to create complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Material Science Precursor: Serves as a building block for functional polymers, liquid crystals, and organic electronic materials due to its conjugated system.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and synthesizing complex heterocyclic libraries.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the thiazole core contributes to color and stability properties.

Basic Information

Product Name	5-Thiazolecarbonitrile, 4-Chloro-
CAS No.	145383-72-8
Molecular Formula	C4HN2ClS
Molecular Weight	144.58 g/mol
Synonyms	4-Chloro-1,3-thiazole-5-carbonitrile; 4-Chlorothiazole-5-carbonitrile; 4-Chloro-5-cyanothiazole; 5-Cyano-4-chlorothiazole; 4-Chloro-thiazole-5-carbonitrile; 145383-72-8; 4-Chloro-1,3-thiazol-5-yl cyanide
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Each batch of 5-Thiazolecarbonitrile, 4-Chloro- is analyzed to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.