Description

5-(1-Adamantylamino)-5-Oxopentanoic Acid is a high-purity, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique structural motif, which imparts desirable properties such as enhanced thermal stability and lipophilicity to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the rigid, bulky adamantyl group into candidate molecules.
• Advanced Material Synthesis: Serves as a precursor for monomers or additives designed to enhance the thermal and mechanical properties of high-performance polymers.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis or as a core structure in organocatalysts.
• Bioconjugation: The carboxylic acid functionality allows for coupling reactions, useful in creating labeled probes or drug conjugates.

Basic Information

Item	Detail
Product Name	5-(1-Adamantylamino)-5-Oxopentanoic Acid
CAS No.	145294-89-9
Molecular Formula	C₁₅H₂₃NO₃
Molecular Weight	265.35 g/mol
Synonyms	5-[(1-Adamantyl)amino]-5-oxopentanoic acid; 5-(Adamantan-1-ylamino)-5-oxopentanoic acid; N-(1-Adamantyl)glutaramide acid; Glutaramide, N-1-adamantyl-; Adamant-1-yl-glutaramide acid; 5-(1-Adamantylcarbamoyl)pentanoic acid; N-Adamantylglutaramic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(1-Adamantylamino)-5-Oxopentanoic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical research and production processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.