Description

1-(3-Chloropropyl)Piperidin-4-Ol is a versatile and high-purity organic building block with a reactive chloropropyl arm and a piperidinol moiety. This compound is critical for the synthesis of complex molecules, offering a strategic point for further functionalization and ring formation. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and advanced chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Chemical Synthesis Building Block: Used for constructing complex heterocyclic compounds and spirocyclic structures via nucleophilic substitution or cyclization reactions.
• Agrochemical Research: Serves as a precursor in the synthesis of experimental herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and chiral auxiliaries in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing specialty polymers with specific functional properties.

Basic Information

Product Name	1-(3-Chloropropyl)Piperidin-4-Ol
CAS No.	145285-36-5
Molecular Formula	C8H16ClNO
Molecular Weight	177.67 g/mol
Synonyms	4-Piperidinol, 1-(3-chloropropyl)-; 1-(3-Chloropropyl)-4-hydroxypiperidine; 4-Hydroxy-1-(3-chloropropyl)piperidine; 1-(3-Chloropropyl)piperidin-4-ol; 1-(γ-Chloropropyl)-4-piperidinol; 4-Piperidinol, 1-(3-chloropropyl)- (9CI); 1-(3-Chloropropyl)-4-piperidinol
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Chloropropyl)Piperidin-4-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.