Description

Biotinyl-Somatostatin-14 CAS NO 145251-83-8 is a biotinylated analog of the neuroendocrine peptide hormone somatostatin-14, designed for high-affinity binding and detection applications. This modification is critical for creating highly specific research and diagnostic tools, enabling advanced studies in receptor biology and signal transduction. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for applications requiring precise molecular targeting and visualization.

Application

• Biochemical Research: Used as a labeled ligand in receptor binding assays and affinity studies for somatostatin receptors (SSTRs).
• Diagnostic Development: Serves as a key component in the development of ELISA, immunohistochemistry (IHC), and other immunoassay kits for detecting somatostatin pathways.
• Drug Discovery: Employed in high-throughput screening (HTS) and target validation during the development of novel therapeutics targeting SSTRs.
• Molecular Imaging Probes: Acts as a targeting moiety for developing advanced imaging conjugates, such as those for fluorescence or radiolabeling in preclinical research.
• Affinity Purification: Utilized in pull-down assays and affinity chromatography for the isolation and study of somatostatin receptor complexes.
• Cell Biology Studies: Applied in flow cytometry and microscopy to study receptor internalization, localization, and expression on cell surfaces.

Basic Information

Product Name	Biotinyl-Somatostatin-14
CAS No.	145251-83-8
Molecular Formula	C78H122N20O19S2
Molecular Weight	1668.1 g/mol
Synonyms	Biotin-Somatostatin-14; Biotin-SST-14; Biotinyl-SST-14; Somatostatin-14 Biotin Conjugate; Biotinylated Somatostatin 14; Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bridge: Cys3-Cys14), Biotinylated; [Biotinyl]-Somatostatin-14; SRIF-14 Biotin Labeled
EINECS	Contact for details

Quality Control

Our Biotinyl-Somatostatin-14 is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized by advanced analytical techniques including HPLC for purity and MS for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and performance data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.