Description

Dnp-Pro-Leu-Gly-Cys(Me)-His-Ala-D-Arg-Nh2 is a synthetic, chemically modified peptide sequence of significant interest in advanced biochemical research and pharmaceutical development. This compound matters as a specialized tool for studying enzyme-substrate interactions, receptor binding, and signal transduction pathways due to its unique structure incorporating a D-arginine residue and a methylated cysteine. It is primarily needed by research institutions, biotechnology companies, and pharmaceutical R&D departments focused on peptide-based drug discovery, protease mechanism studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study protease specificity and kinetics.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of peptide-based therapeutics targeting specific biological pathways.
• Proteomics & Signal Transduction: Employed to investigate protein-protein interactions and cellular signaling mechanisms.
• Academic Research: Utilized in university laboratories for fundamental studies in peptide chemistry, molecular biology, and medicinal chemistry.
• Biomarker Development: Potential use in the design and calibration of assays for detecting specific enzymatic activities.

Basic Information

Product Name	Dnp-Pro-Leu-Gly-Cys(Me)-His-Ala-D-Arg-Nh2
CAS No.	145224-98-2
Molecular Formula	C41H62N14O10S
Molecular Weight	919.08 g/mol
Synonyms	DNP-Pro-Leu-Gly-Cys(Me)-His-Ala-D-Arg-NH2; 2,4-Dinitrophenyl-Pro-Leu-Gly-Cys(Methyl)-His-Ala-D-Arg-Amide; H-D-Arg-NH2 modified peptide; Dnp-Pro-Leu-Gly-Cys(Me)-His-Ala-D-Arg-amide; Methylcysteine-containing peptide; Protease substrate analog; DNP-labeled peptide; Custom synthetic peptide 145224-98-2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Dnp-Pro-Leu-Gly-Cys(Me)-His-Ala-D-Arg-Nh2 is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity (HPLC), molecular weight confirmation (MS), and related substances are available upon request. We adhere to a quality management system to support research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For short-term use, store at 2-8°C. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.