Description

H-Asp-Asp-Asp-Asp-Oh (CAS NO 145224-95-9) is a high-purity tetrapeptide composed of four aspartic acid residues, serving as a critical building block in advanced biochemical research and pharmaceutical development. This compound is valued for its role in mimicking polyanionic sequences and studying protein-protein interactions, particularly in areas involving calcium binding and mineralization processes. It is primarily utilized by researchers and manufacturers in the biotechnology, pharmaceutical, and advanced materials sectors for peptide synthesis, diagnostic reagent development, and as a reference standard.

Application

• Biochemical Research: Used as a model compound for studying poly-aspartic acid sequences, protein folding, and biomimetic mineralization.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of more complex therapeutic peptides and peptidomimetics.
• Diagnostic Reagents: Employed in the development of calibration standards and reagents for diagnostic assays targeting specific peptide sequences.
• Biomaterials Development: Investigated for use in creating bio-inspired materials, such as coatings for medical implants that influence calcium deposition.
• Enzyme Substrate Studies: Acts as a substrate or inhibitor in enzymatic studies, particularly for proteases and kinases.
• Cosmeceutical Research: Explored in advanced skincare research for its potential role in signal transduction and skin barrier function.

Basic Information

Product Name	H-Asp-Asp-Asp-Asp-Oh
CAS No.	145224-95-9
Molecular Formula	C16H24N4O13
Molecular Weight	504.38 g/mol
Synonyms	Aspartic Acid Tetramer; Poly-L-aspartic Acid (n=4); H-Asp-Asp-Asp-Asp-OH; Asp4; L-Aspartic Acid Tetrapeptide; (L-Asp)4; Tetrakis(L-aspartic acid); Aspartic Acid Homotetramer
EINECS	Contact for details

Quality Control

Our H-Asp-Asp-Asp-Asp-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.