Description

(S)-(-)-2,2'-Bis(Di-2-Furanylphosphino)-6,6'-Dimethoxy-1,1'-Biphenyl, Min. 97% is a high-purity, chiral bisphosphine ligand, a critical component in asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, which are essential for the efficient and sustainable synthesis of single-enantiomer pharmaceutical intermediates and fine chemicals. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-performance ligands for transition metal-catalyzed reactions like hydrogenation and cross-coupling.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Used in the catalytic synthesis of single-enantiomer active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Agrochemical Production: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Cross-Coupling Reactions: Facilitates asymmetric versions of Suzuki, Heck, and other C-C bond-forming reactions.
• Academic & Industrial R&D: A valuable tool for methodology development in academic laboratories and for scaling up novel catalytic processes in industry.
• Fine Chemical Manufacturing: Critical for producing high-value, optically pure flavors, fragrances, and electronic chemicals.

Basic Information

Product Name	(S)-(-)-2,2'-Bis(Di-2-Furanylphosphino)-6,6'-Dimethoxy-1,1'-Biphenyl, Min. 97%
CAS No.	145214-59-1
Molecular Formula	C34H28O6P2
Molecular Weight	602.52 g/mol
Synonyms	(S)-(-)-2,2'-Bis(di-2-furylphosphino)-6,6'-dimethoxy-1,1'-biphenyl; (S)-Bis(di-2-furylphosphino)-6,6'-dimethoxy-1,1'-biphenyl; (S)-(-)-2,2'-Bis(di-2-furylphosphino)-6,6'-dimethoxybiphenyl; (S)-DTBM-SEGPHOS; (S)-DTBM-SegPhos; (S)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole (common mis-assignment check); SEGPHOS derivative; Chiral bisphosphine ligand.
EINECS	Contact for details

Quality Control

Our (S)-(-)-2,2'-Bis(Di-2-Furanylphosphino)-6,6'-Dimethoxy-1,1'-Biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and 31P NMR, to ensure a minimum purity of 97% and correct stereochemical integrity. Certificates of Analysis (COA) with full specification data are provided to guarantee consistency and reliability for your critical catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or ambient temperature may lead to degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0% ee
Water Content (KF)	Max. 0.5%
Residue on Ignition	Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.