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(R)-(+)-2,2'-Bis(Di-2-Furanylphosphino)-6,6'-Dimethoxy-1,1'-Biphenyl,Min.97% CAS NO 145214-57-9
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CAS No.:145214-57-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-(+)-2,2'-Bis(Di-2-Furanylphosphino)-6,6'-Dimethoxy-1,1'-Biphenyl, Min. 97% is a high-purity, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing single-enantiomer intermediates and active pharmaceutical ingredients (APIs). This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and effective ligands for complex synthetic transformations.
Application
- As a chiral ligand for asymmetric hydrogenation reactions, a key step in synthesizing chiral amines, amino acids, and alcohols.
- Catalyst component in asymmetric C-C bond-forming reactions, such as cross-couplings and allylic substitutions.
- Critical reagent in the research and development of novel pharmaceutical candidates, enabling the creation of enantiomerically pure drug molecules.
- Use in process chemistry for the scale-up and optimization of API manufacturing routes.
- Application in agrochemical synthesis for producing chiral herbicides, fungicides, and insecticides.
- Tool in academic and industrial research to explore new catalytic methodologies and reaction mechanisms.
Basic Information
| Product Name | (R)-(+)-2,2'-Bis(Di-2-Furanylphosphino)-6,6'-Dimethoxy-1,1'-Biphenyl, Min. 97% |
| CAS No. | 145214-57-9 |
| Molecular Formula | C34H28O6P2 |
| Molecular Weight | 602.52 g/mol |
| Synonyms | (R)-(+)-2,2'-Bis(di-2-furanylphosphino)-6,6'-dimethoxy-1,1'-biphenyl; (R)-DTBM-SEGPHOS; (R)-DTBM-SegPhos; (R)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole; (R)-DTBM-SEGPHOS Ligand; (R)-DTBM-Segphos; (R)-2,2'-Bis(di-2-furylphosphino)-6,6'-dimethoxy-1,1'-biphenyl; (R)-DTBM-SegPhos (Ligand) |
| EINECS | Contact for details |
Quality Control
Our (R)-DTBM-SEGPHOS is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow powder or crystals |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | Min. 97.0% |
| Specific Rotation | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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