Description

Boc-L-2-Furylalanine Dcha Salt is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. Its primary value lies in providing a sterically hindered, non-proteinogenic amino acid scaffold for constructing complex peptides and peptidomimetics with enhanced metabolic stability. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel therapeutic agents and conducting advanced peptide research.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to incorporate the unique 2-furylalanine side chain into peptide backbones to study structure-activity relationships and improve drug-like properties.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected amino acid monomer for the automated synthesis of custom peptides containing non-natural amino acids.
• Medicinal Chemistry: Employed in lead optimization to enhance the potency, selectivity, and pharmacokinetic profile of peptide candidates.
• Bioconjugation: The Boc-protected amine and carboxylic acid functionalities allow for selective conjugation to other molecules or surfaces.
• Chemical Biology Probes: Useful for creating labeled or modified peptides to study biological processes and protein-protein interactions.

Basic Information

Product Name	Boc-L-2-Furylalanine Dcha Salt
CAS No.	145206-40-2
Molecular Formula	C₂₂H₃₆N₂O₅
Molecular Weight	408.54 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-(2-furyl)-L-alanine dicyclohexylamine salt; Boc-FurAla-OH·DCHA; Boc-L-β-(2-Furyl)alanine DCHA salt; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(furan-2-yl)propanoic acid - dicyclohexylamine (1:1); tert-Butoxycarbonyl-3-(2-furyl)-L-alanine dicyclohexylammonium salt; Boc-L-Furylalanine DCHA; N-Boc-3-(2-furanyl)-L-alanine dicyclohexylamine salt
EINECS	Contact for details

Quality Control

Our Boc-L-2-Furylalanine Dcha Salt is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.