Description

Glycophorin-Binding Protein Homologue, Plasmodium is a specialized recombinant protein derived from *Plasmodium* species, the causative agents of malaria. This protein is critical for research focused on understanding the molecular mechanisms of host cell invasion, particularly the interaction between the malaria parasite and human erythrocyte surface glycophorins. It serves as an essential reagent for scientists and developers in the fields of parasitology, vaccine development, and novel antimalarial drug discovery, enabling high-throughput screening and functional studies.

Application

• Parasitology Research: Fundamental tool for studying the molecular biology of *Plasmodium* merozoite invasion and host-parasite interactions.
• Vaccine Antigen Candidate: Used in the research and development of subunit vaccines targeting the blood stage of malaria.
• Drug Discovery Platform: Employed in high-throughput screening assays to identify and validate novel compounds that inhibit parasite adhesion and invasion.
• Diagnostic Development: Serves as a coating antigen or target in the development of immunoassays and biosensors for malaria detection.
• Structural Biology Studies: Provides material for X-ray crystallography, NMR, and cryo-EM to elucidate the protein's 3D structure and binding epitopes.
• Antibody Production & Characterization: Used as an immunogen to generate monoclonal or polyclonal antibodies for therapeutic or diagnostic applications.

Basic Information

Product Name	Glycophorin-Binding Protein Homologue, Plasmodium
CAS No.	145169-58-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GBPH, Plasmodium GBPH; Glycophorin binding protein; Merozoite surface protein homolog; Erythrocyte-binding antigen; EBA-175 homolog; *Plasmodium falciparum* GBPH; Malaria invasion protein; Recombinant GBPH
EINECS	Contact for details

Quality Control

Our recombinant protein products are manufactured under stringent quality management systems. Each batch is subjected to a comprehensive suite of analytical tests, including SDS-PAGE, Western Blot, and functional binding assays, to ensure high purity, identity, and biological activity. Certificates of Analysis (COA) detailing purity, endotoxin levels, and buffer composition are provided with every shipment. Production can be aligned with research-grade or GMP-grade standards upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the vial is at room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE & Western Blot)	Single band at expected molecular weight
Purity (SDS-PAGE, reduced)	≥ 90%
Protein Content (UV Absorbance / BCA)	≥ 95% of stated mass
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA / SPR)	Binds specifically to glycophorin A/B
Solubility	Soluble in PBS or specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.