Description

Glutamate-Rich Protein, Plasmodium is a specific protein fraction derived from *Plasmodium* species, characterized by a high content of the amino acid glutamate. This biochemical is a critical research tool for understanding malaria parasite biology, particularly in studies of antigenic variation, host-cell invasion, and immune evasion mechanisms. It is essential for researchers and developers in the fields of parasitology, vaccine development, and diagnostic assay design, providing a purified target for immunological and biochemical studies. CAS No. 145112-81-8.

Application

• Malaria Research & Development: Fundamental research into *Plasmodium falciparum* and other malaria parasite biology, life cycle, and pathogenesis.
• Antigen for Immunoassays: Used as a coating antigen or standard in enzyme-linked immunosorbent assays (ELISAs), Western blotting, and other immunoassays to detect specific antibodies.
• Vaccine Candidate Evaluation: Serves as a key antigenic target in preclinical studies for evaluating novel malaria vaccine candidates and adjuvants.
• Parasite-Host Interaction Studies: Investigation of molecular mechanisms involved in red blood cell invasion and modulation of the host immune response.
• Diagnostic Kit Development: A critical raw material for the development and quality control of rapid diagnostic tests (RDTs) and other point-of-care diagnostic tools for malaria.
• Biochemical Standard: Acts as a purified protein standard for proteomic analysis, protein characterization, and method validation in research laboratories.

Basic Information

Product Name	Glutamate-Rich Protein, Plasmodium
CAS No.	145112-81-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Plasmodium Glutamate-Rich Protein; GRP; PfGRP; Glutamate-Rich Antigen; Malaria Glutamate-Rich Protein; Plasmodium falciparum Glutamate-Rich Protein; MERP (Merozoite Glutamate-Rich Protein); Antigen GLURP
EINECS	Contact for details

Quality Control

Our Glutamate-Rich Protein, Plasmodium is produced and handled under stringent quality protocols suitable for research and in-vitro diagnostic (IVD) use. Each batch undergoes comprehensive analytical testing including purity assessment by SDS-PAGE and HPLC, identity confirmation via immunoblotting or mass spectrometry, and quantification. Certificates of Analysis (COA) detailing batch-specific results for purity, identity, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Immunoblot)	Conforms
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of dry weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers
Biological Activity (ELISA)	Reactive with specific antisera

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.