Description

1,1,2,2-Tetrafluoro-2-(1,1,2,2-Tetrafluoroethoxy)-Ethanesulfonyl Azide is a specialized fluorinated sulfonyl azide compound, a key intermediate for introducing sulfonyl azide functional groups into target molecules. Its value lies in enabling efficient click chemistry and cross-linking reactions under mild conditions, which is critical for advanced material synthesis. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries developing novel fluorinated compounds, surface modifiers, and high-performance materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel fluorinated drug candidates and bioactive molecules, leveraging the sulfonyl azide group for bioconjugation.
• Polymer & Material Science: Serves as a cross-linking agent or functional monomer for creating fluorinated polymers, coatings, and membranes with enhanced chemical resistance and surface properties.
• Surface Modification: Enables the covalent attachment of functional layers to various substrates (e.g., silicon, metals, polymers) for creating tailored surface chemistries.
• Agrochemical Synthesis: Acts as a building block for developing advanced fluorinated pesticides and herbicides with improved efficacy and environmental profiles.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and other bioorthogonal reactions for labeling and constructing complex molecular architectures.
• Lithography & Photoresists: Potential application in advanced photoresist formulations for semiconductor manufacturing due to its photoactive azide group and fluorinated structure.

Basic Information

Product Name	1,1,2,2-Tetrafluoro-2-(1,1,2,2-Tetrafluoroethoxy)-Ethanesulfonyl Azide
CAS No.	144951-88-2
Molecular Formula	C4HF8N3O3S
Molecular Weight	323.12 g/mol
Synonyms	1,1,2,2-Tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)ethanesulfonyl azide; Tetrafluoro(1,1,2,2-tetrafluoroethoxy)ethanesulfonyl azide; 2-(1,1,2,2-Tetrafluoroethoxy)-1,1,2,2-tetrafluoroethanesulfonyl azide; Perfluoro(2-ethoxyethane)sulfonyl azide; F-EES-Azide; TFESA; Ethanesulfonyl azide, 1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoroethoxy)-
EINECS	Contact for details

Quality Control

Our 1,1,2,2-Tetrafluoro-2-(1,1,2,2-Tetrafluoroethoxy)-Ethanesulfonyl Azide is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, IR, and HPLC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and industrial applications, with quality systems designed to support cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.