Description

Guanylin (Rat) is a synthetic peptide hormone analog that plays a crucial role in regulating intestinal fluid and electrolyte homeostasis. This high-purity compound is essential for advanced biochemical and pharmacological research, particularly in studies of guanylate cyclase-C (GC-C) receptor signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on gastroenterology, renal physiology, and novel therapeutic development.

Application

• Biomedical Research: Fundamental studies on intestinal salt and water transport mechanisms.
• Drug Discovery: Target validation and screening for GC-C receptor agonists/antagonists in metabolic and gastrointestinal disorders.
• Physiological Studies: Investigation of renal and cardiovascular functions linked to natriuretic peptide systems.
• In Vitro Assay Development: Used as a reference standard in cell-based assays and receptor binding studies.
• Academic Research: Tool compound for graduate and post-doctoral research in molecular biology and peptide pharmacology.

Basic Information

Item	Details
Product Name	Guanylin (Rat)
CAS No.	144940-98-7
Molecular Formula	C53H74N18O19S4
Molecular Weight	1363.5 g/mol
Synonyms	Rat Guanylin; Guanylin Rodent; Guanylin (15-21), rat; H-Pro-Asn-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bridge: Cys4-Cys12, Cys7-Cys15); ST peptide (guanylin); Heat-stable enterotoxin receptor ligand; GC-C agonist peptide; GUAR
EINECS	Contact for details

Quality Control

Every batch of Guanylin (Rat) is manufactured and analyzed under strict quality management protocols to ensure the highest standards of purity and biological activity. Our quality control includes comprehensive characterization by HPLC, MS, and amino acid analysis. A detailed Certificate of Analysis (COA) documenting purity, peptide content, and endotoxin levels is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Molecular Weight	1363.5 ± 2 Da
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%
Endotoxin Level	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.