Description

3,11,17-Trioxoandrostane-5-Carbonitrile is a high-purity synthetic steroid derivative characterized by its specific nitrile and trioxo functional groups. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Research Chemical: Used in biochemical and pharmacological research to study structure-activity relationships (SAR) of steroid molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Precursor for Drug Discovery: Utilized in medicinal chemistry for the development of potential therapeutics targeting hormone receptors or metabolic pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for introducing specific functional groups into complex molecular frameworks.

Basic Information

Product Name	3,11,17-Trioxoandrostane-5-Carbonitrile
CAS No.	144940-53-4
Molecular Formula	C20H25NO3
Molecular Weight	327.42 g/mol
Synonyms	5-Cyano-3,11,17-trioxoandrostane; Androstane-5-carbonitrile, 3,11,17-trioxo-; 3,11,17-Trioxoandrost-5-ene-5-carbonitrile (related structure); 5-Cyanoandrostane-3,11,17-trione; Steroid Nitrile Intermediate; 5-CN-Androstane-trione
EINECS	Contact for details

Quality Control

Our 3,11,17-Trioxoandrostane-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.