Description

Methyl 3-Amino-4-Fluorobenzo[B]Thiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique benzo[b]thiophene core provides a versatile scaffold. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency and reliability for your sensitive processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting various therapeutic areas, including central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Dye and Pigment Manufacturing: Intermediate for creating specialized fluorinated heterocyclic dyes with unique optical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects requiring a fluorinated aminothiophene carboxylate moiety.

Basic Information

Product Name	Methyl 3-Amino-4-Fluorobenzo[B]Thiophene-2-Carboxylate
CAS No.	144899-95-6
Molecular Formula	C10H8FNO2S
Molecular Weight	225.24 g/mol
Synonyms	Methyl 3-amino-4-fluorobenzo[b]thiophene-2-carboxylate; 3-Amino-4-fluorobenzo[b]thiophene-2-carboxylic acid methyl ester; 4-Fluoro-3-aminobenzo[b]thiophene-2-carboxylic acid methyl ester; Methyl 4-fluoro-3-aminobenzo[b]thiophene-2-carboxylate; 2-Carbomethoxy-3-amino-4-fluorobenzo[b]thiophene; 144899-95-6; Methyl 3-amino-4-fluorobenzo[b]thien-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-4-Fluorobenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure full traceability and compliance with your internal quality standards and research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.