Description

1,3-Difluoro-5-Ethoxybenzene is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring fluorine and ethoxy substituents in a meta-relationship, makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine atoms enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers and resins with improved chemical resistance.
• Chemical Research & Development: A versatile reagent for exploring new reaction pathways and creating novel fluorinated compounds in academic and industrial labs.
• Dye & Pigment Manufacturing: Utilized in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	1,3-Difluoro-5-Ethoxybenzene
CAS No.	144891-25-8
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	5-Ethoxy-1,3-difluorobenzene; 3,5-Difluorophenetole; 1-Ethoxy-3,5-difluorobenzene; Benzene, 1,3-difluoro-5-ethoxy-; 3,5-Difluorophenyl ethyl ether; 144891-25-8; 5-Ethoxy-m-difluorobenzene; m-Difluoro-5-ethoxybenzene
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-5-Ethoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency that meets the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.15 g/cm³
Refractive Index (n20D)	~1.460

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.