Description

Fmoc-Dl-Proline CAS NO 144829-96-9 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). It serves as a critical building block for the controlled introduction of proline residues, enabling the production of complex peptides and peptidomimetics with precise stereochemistry. This compound is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental N-α-Fmoc protected amino acid for the automated synthesis of peptides and proteins.
• Pharmaceutical Research: Used in the development of peptide-based drugs, including hormone analogs, enzyme inhibitors, and receptor agonists/antagonists.
• Combinatorial Chemistry: Serves as a key reagent in libraries for high-throughput screening to discover new bioactive compounds.
• Bioconjugation: Acts as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Academic & Biochemical Research: Employed in studies of protein folding, structure-activity relationships (SAR), and molecular recognition.
• Production of Custom Peptides: Essential for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke peptide services.

Basic Information

Product Name	Fmoc-Dl-Proline
CAS No.	144829-96-9
Molecular Formula	C₂₀H₁₉NO₄
Molecular Weight	337.37 g/mol
Synonyms	Fmoc-DL-Pro-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-DL-proline; (RS)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic Acid; DL-Fmoc-Proline; N-Fmoc-DL-proline; Fmoc-DL-Pro; FMOC-DL-PROLINE; N-α-Fmoc-DL-proline
EINECS	Contact for details

Quality Control

Our Fmoc-Dl-Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, to ensure it meets the stringent requirements for peptide synthesis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.