Description

Complement Receptor-Related Protein CAS NO 144714-47-6 is a high-purity biochemical reagent of significant interest in immunological research and therapeutic development. This protein plays a crucial role in modulating the complement system, a key component of innate immunity and inflammatory responses. It is primarily utilized by research institutions and biopharmaceutical companies engaged in the study of autoimmune diseases, inflammatory disorders, and the development of novel immunotherapies.

Application

• Biomedical Research: Used as a critical reagent for studying the activation, regulation, and signaling pathways of the complement system in vitro.
• Drug Discovery & Development: Serves as a target protein for screening and validating potential therapeutic compounds aimed at modulating complement activity.
• Diagnostic Assay Development: Employed in the development and calibration of immunoassays (e.g., ELISA) to detect complement-related biomarkers in clinical samples.
• Autoimmune Disease Studies: Essential for investigating the pathological role of complement dysregulation in conditions like lupus, rheumatoid arthritis, and atypical hemolytic uremic syndrome (aHUS).
• Inflammation Research: Applied in models to understand the link between complement activation and chronic inflammatory processes.
• Biopharmaceutical Production: May be used as a reference standard or quality control material in the production of antibody-based or protein-based therapeutics targeting the complement pathway.

Basic Information

Product Name	Complement Receptor-Related Protein
CAS No.	144714-47-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CRRP; Complement Receptor Related Protein; Complement Regulatory Protein (context-dependent); sCR1 (Soluble Complement Receptor 1) fragment/analogue (potential); Immunomodulatory Protein; Complement Inhibitor Protein; C3b/C4b Inactivator related protein
EINECS	Contact for details

Quality Control

Our Complement Receptor-Related Protein is manufactured under stringent conditions to ensure high batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation, and endotoxin level testing. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (HPLC)	≥ 95%
Protein Content (UV)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/mg
Biological Activity (Functional Assay)	Contact for details
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.