Description

Collagen Type II Fragment is a specific, enzymatically derived peptide sequence sourced from native type II collagen, a primary structural protein in articular cartilage. This high-purity fragment is critical for research and development in the life sciences, particularly for its role in modulating immune responses related to joint health. It is an essential raw material for manufacturers in the pharmaceutical, nutraceutical, and biomedical research sectors, where precise biological activity and batch-to-batch consistency are paramount.

Application

• Active Pharmaceutical Ingredient (API) in the development of therapies for autoimmune joint conditions.
• Key Intermediate for the synthesis of advanced nutraceuticals and dietary supplements targeting cartilage support.
• Biomedical Research Reagent for in vitro and in vivo studies on collagen metabolism, immunology, and osteoarthritis.
• Reference Standard in quality control laboratories for the assay and identification of collagen-based products.
• Biomaterial Component in the engineering of scaffolds for cartilage tissue repair and regenerative medicine.
• Formulation Ingredient in topical applications and cosmeceuticals designed for skin and joint health.

Basic Information

Product Name	Collagen Type II Fragment
CAS No.	144703-90-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Collagen II Peptide; Type II Collagen Fragment; Chondroprotective Peptide; Cartilage Collagen Peptide; UC-II® related fragment; Collagen Hydrolysate (Type II); CII Fragment; Immunomodulatory Collagen Peptide
EINECS	Contact for details

Quality Control

Our Collagen Type II Fragment is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and peptide mapping, amino acid analysis, and biological activity assays, to ensure it meets the stringent requirements for research and GMP-grade manufacturing. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 95.0%
Peptide Content	≥ 90.0% (by weight)
Amino Acid Profile	Characteristic of Type II Collagen
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Biological Activity	Confirmed by ELISA or cell-based assay
Microbial Limits	Meets Ph. Eur. 2.6.12/2.6.13
Endotoxin	< 10.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.