Description

Flt4 Protein CAS NO 144638-77-7 is a high-purity recombinant protein, also known as Vascular Endothelial Growth Factor Receptor 3 (VEGFR-3), which plays a critical role in the regulation of lymphangiogenesis. This product is essential for researchers and developers in the life sciences sector, providing a reliable and well-characterized reagent for advanced studies. It is primarily utilized in biochemical research, drug discovery, and the development of diagnostic assays targeting lymphatic system pathways and related cancers.

Application

• Biochemical Research: Used as a key reagent in studying lymphangiogenesis, vascular biology, and receptor-ligand interactions.
• Drug Discovery & Development: Serves as a target protein for screening and validating potential therapeutic compounds, particularly in oncology for anti-lymphangiogenic therapies.
• Diagnostic Assay Development: Employed in the development of immunoassays (ELISA) and other diagnostic kits to detect and quantify VEGFR-3/Flt4 related biomarkers.
• Cell Signaling Studies: Utilized to investigate intracellular signaling pathways mediated by the VEGFR-3 receptor in various cell culture models.
• Protein-Protein Interaction Analysis: Acts as a bait or prey protein in pull-down assays, surface plasmon resonance (SPR), and other interaction studies.
• Antibody Production & Validation: Used as an immunogen for generating monoclonal or polyclonal antibodies specific to the VEGFR-3 receptor.

Basic Information

Item	Details
Product Name	Flt4 Protein
CAS No.	144638-77-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	VEGFR-3; Vascular Endothelial Growth Factor Receptor 3; Fms Related Receptor Tyrosine Kinase 4; FLT4 Receptor; Tyrosine-protein kinase receptor FLT4; FLT-4; VEGFR3; hFLT4; Fms-like tyrosine kinase 4; Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1) related protein; Recombinant Human VEGFR-3/Flt-4 Fc Chimera
EINECS	Contact for details

Quality Control

Our Flt4 Protein is manufactured under stringent quality systems. Each batch undergoes rigorous analytical testing, including purity assessment by SDS-PAGE and HPLC, endotoxin level determination, and functional activity verification to ensure consistency and reliability for your critical research. A comprehensive Certificate of Analysis (COA) detailing purity, concentration, biological activity, and sterility (where applicable) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	> 95%
Purity (HPLC)	> 98%
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Determined by cell-based assay or ligand binding
Formulation	Lyophilized from a sterile solution
Reconstitution	Consult COA for specific buffer recommendations

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.