Description

Egr3 Protein CAS NO 144516-98-3 is a recombinant protein corresponding to the early growth response protein 3, a zinc-finger transcription factor involved in critical cellular signaling pathways. This high-purity protein is essential for advanced life science research, enabling the study of neuronal development, immune response, and synaptic plasticity. It is a vital reagent for molecular biologists, neuroscientists, and pharmaceutical researchers engaged in target validation, assay development, and mechanistic studies of gene regulation.

Application

• Biochemical Research: Used as a standard or antigen in studies of transcription factor function, DNA-protein interactions, and signal transduction pathways.
• Neuroscience Studies: Critical for investigating its role in activity-dependent gene expression, long-term potentiation (LTP), and neuronal differentiation.
• Immunology Research: Applied in research exploring T-cell activation, cytokine signaling, and immune system regulation.
• Assay Development: Serves as a key component in developing ELISA, Western blot, and electrophoretic mobility shift assays (EMSAs) for diagnostic and research purposes.
• Drug Discovery: Utilized in high-throughput screening (HTS) campaigns to identify novel modulators of Egr3 activity for therapeutic intervention.
• Protein-Protein Interaction Studies: Employed in pull-down assays, co-immunoprecipitation, and yeast two-hybrid screens to map interactomes.

Basic Information

Product Name	Egr3 Protein
CAS No.	144516-98-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Early Growth Response Protein 3; EGR-3; Krox-20; Zif268; NGFI-A; ZENK; AT225; KROX20; Recombinant Human Egr3 Protein; Transcription Factor Egr3; Zinc Finger Protein 225
EINECS	Contact for details

Quality Control

Our Egr3 Protein is manufactured under stringent conditions to ensure the highest standards of purity, identity, and biological activity. Each batch is subjected to a comprehensive battery of analytical tests, including SDS-PAGE, Western blot, mass spectrometry, and functional activity assays. A Certificate of Analysis (COA) detailing purity, concentration, endotoxin levels, and specific activity is provided with every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the vial is equilibrated to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	≥ 95%
Identification (Western Blot)	Positive
Endotoxin Level (LAL)	< 1.0 EU/µg
Protein Concentration	Verified by UV absorbance
Biological Activity	Assay-dependent; confirmed by functional assay
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.