Description

Cyclohexanone, 2-Fluoro-2-(Hydroxymethyl)-, (S)- (9Ci) is a high-value, chiral fluorinated building block essential for advanced organic synthesis. This compound matters for its unique stereochemistry and functional groups, enabling the precise construction of complex molecules with defined three-dimensional architecture. It is primarily needed by pharmaceutical and agrochemical R&D teams for developing novel active ingredients, as well as by fine chemical manufacturers producing specialty intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where the specific (S)-enantiomer imparts desired biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals for electronics and material science applications.
• Academic and Industrial Research: A valuable tool for methodological studies in organic chemistry, exploring new fluorination and C-C bond forming reactions.

Basic Information

Product Name	Cyclohexanone, 2-Fluoro-2-(Hydroxymethyl)-, (S)- (9Ci)
CAS No.	144462-31-7
Molecular Formula	C7H11FO2
Molecular Weight	146.16 g/mol
Synonyms	(S)-2-Fluoro-2-(hydroxymethyl)cyclohexanone; (S)-2-(Fluoromethyl)-2-hydroxycyclohexanone; 2-Fluoro-2-(hydroxymethyl)cyclohexanone, (S)-; (S)-2-Fluoromethyl-2-hydroxycyclohexanone; 144462-31-7; (S)-α-Fluoromethyl-α-hydroxycyclohexanone; (S)-1-(Fluoromethyl)-1-hydroxycyclohexan-2-one
EINECS	Contact for details

Quality Control

Our Cyclohexanone, 2-Fluoro-2-(Hydroxymethyl)-, (S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid or colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.