Description

3-Chloro-4-Fluorophenylboronic Acid is a high-purity organoboron compound, a key building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex biaryl and heterobiaryl structures. This versatile intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex biaryl motifs for oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides by constructing the core aromatic frameworks of these molecules.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Advanced Material Precursor: Employed in the research and development of organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new carbon-carbon bond-forming methodologies and library synthesis.
• Custom Synthesis: Used by fine chemical manufacturers for the contract synthesis of bespoke, high-value organic compounds for various industries.

Basic Information

Product Name	3-Chloro-4-Fluorophenylboronic Acid
CAS No.	144432-85-9
Molecular Formula	C6H5BClFO2
Molecular Weight	173.37 g/mol
Synonyms	(3-Chloro-4-fluorophenyl)boronic acid; 3-Chloro-4-fluorobenzeneboronic acid; B-(3-Chloro-4-fluorophenyl)boronic acid; 3-Chloro-4-fluoro-benzeneboronic acid; 144432-85-9; Boronic acid, B-(3-chloro-4-fluorophenyl)-; 3-Chloro-4-fluorophenyl-Boronic Acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.