Description

n-Bromoacetyl-Phenylalanyl-Leucyl-Glutamyl-Glutamyl-Leucyl-Tyrosine is a synthetic, bromoacetylated hexapeptide derivative designed for advanced biochemical research and pharmaceutical development. This compound serves as a critical intermediate or building block for the synthesis of more complex molecules, particularly in the field of targeted drug discovery and proteomics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on enzyme inhibitors, affinity labeling, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel peptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate protease mechanisms and kinetics.
• Affinity Labeling Probe: The bromoacetyl group acts as an electrophile for the covalent modification of active-site residues in target proteins, enabling protein function and interaction studies.
• Proteomics Tool: Employed in the design and development of activity-based probes (ABPs) for profiling enzyme activities in complex biological samples.
• Peptide Library Synthesis: A valuable component in combinatorial chemistry for creating diverse peptide libraries to screen for biological activity.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and chemical biology.

Basic Information

Product Name	n-Bromoacetyl-Phenylalanyl-Leucyl-Glutamyl-Glutamyl-Leucyl-Tyrosine
CAS No.	144304-34-7
Molecular Formula	C43H60BrN7O14
Molecular Weight	1003.88 g/mol
Synonyms	Bromoacetyl-Phe-Leu-Glu-Glu-Leu-Tyr-OH; BrAc-FLEELY; N-Bromoacetyl-Phe-Leu-Glu-Glu-Leu-Tyrosine; Bromoacetyl Hexapeptide; FLEELY(BrAc); (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-(2-Bromoacetamido)-3-phenylpropanamido]-4-methylpentanamido]-4-carboxybutanamido]-4-carboxybutanamido]-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our n-Bromoacetyl-Phenylalanyl-Leucyl-Glutamyl-Glutamyl-Leucyl-Tyrosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.