Description

1-(Benzyloxy)-2,3-Difluorobenzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a benzyl-protected phenolic oxygen and strategically placed fluorine atoms, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the difluorobenzene core can enhance biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs), contributing to improved performance and stability.
• Polymer & Specialty Chemicals: Employed as a monomer or modifier in the production of high-performance polymers, coatings, and specialty chemicals requiring specific aromatic fluorine content.
• Chemical Research & Development: A valuable building block in academic and industrial labs for methodological studies in cross-coupling reactions, etherification, and fluorination chemistry.

Basic Information

Product Name	1-(Benzyloxy)-2,3-Difluorobenzene
CAS No.	144292-53-5
Molecular Formula	C₁₃H₁₀F₂O
Molecular Weight	220.22 g/mol
Synonyms	2,3-Difluorophenyl benzyl ether; Benzyl 2,3-difluorophenyl ether; 2,3-Difluorophenyl benzyl ether; 1-(Benzyloxy)-2,3-difluorobenzene; (2,3-Difluorophenoxy)methyl]benzene; o-Difluorophenyl benzyl ether; NSC 405124; BDFB
EINECS	Contact for details

Quality Control

Every batch of 1-(Benzyloxy)-2,3-Difluorobenzene is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.