Description

1-Ethoxy-2,3-Difluoro-4-Iodobenzene is a high-value, multi-functional halogenated aromatic building block. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules for the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated and iodinated drug candidates, leveraging the ethoxy and halogen substituents for structural diversity and bioactivity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides where the difluoro and iodo groups impart specific biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the synthesis of conjugated molecules and polymers for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form complex biaryl structures.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	1-Ethoxy-2,3-Difluoro-4-Iodobenzene
CAS No.	144292-42-2
Molecular Formula	C8H7F2IO
Molecular Weight	284.05 g/mol
Synonyms	2,3-Difluoro-4-iodo-1-ethoxybenzene; 4-Iodo-2,3-difluoro-1-ethoxybenzene; 1-Ethoxy-2,3-difluoro-4-iodobenzene; Benzene, 1-ethoxy-2,3-difluoro-4-iodo-; 2,3-Difluoro-4-iodophenetole
EINECS	Contact for details

Quality Control

Our 1-Ethoxy-2,3-Difluoro-4-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.