Description

2,3-Difluoro-1-(hexyloxy)-4-iodobenzene is a high-purity, multi-functional halogenated aromatic building block. This compound matters for its unique molecular architecture, combining fluorine, iodine, and an alkoxy chain, which makes it a versatile intermediate for constructing complex molecules in advanced research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki cross-coupling reactions and the synthesis of liquid crystals or organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring fluorinated and iodinated aromatic cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the difluoro and iodo substituents can modulate biological activity and stability.
• Cross-Coupling Reactions: Serves as an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the reactive iodine atom.
• Liquid Crystal & OLED Materials: A building block for creating advanced organic materials used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in organic synthesis for introducing specific fluorinated and alkoxylated motifs into more complex molecular frameworks.
• Research & Development: A valuable tool for academic and industrial R&D in exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	2,3-Difluoro-1-(Hexyloxy)-4-Iodobenzene
CAS No.	144292-41-1
Molecular Formula	C12H15F2IO
Molecular Weight	340.15 g/mol
Synonyms	1-(Hexyloxy)-2,3-difluoro-4-iodobenzene; 4-Iodo-2,3-difluorophenyl hexyl ether; Benzene, 2,3-difluoro-1-(hexyloxy)-4-iodo-; 2,3-Difluoro-4-iodophenyl hexyl ether; 2,3-Difluoro-1-hexyloxy-4-iodobenzene
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-1-(hexyloxy)-4-iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.